
3-Phosphoglyceric acid
CAS No. 820-11-1
3-Phosphoglyceric acid( —— )
Catalog No. M33584 CAS No. 820-11-1
3-Phosphoglyceric acid is a metabolic intermediate in glycolysis and the Calvin cycle, and it is also involved in alveolar macrophage epigenetic regulation.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 347 | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product Name3-Phosphoglyceric acid
-
NoteResearch use only, not for human use.
-
Brief Description3-Phosphoglyceric acid is a metabolic intermediate in glycolysis and the Calvin cycle, and it is also involved in alveolar macrophage epigenetic regulation.
-
Description3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid is involved in alveolar macrophage epigenetic regulation.
-
In Vitro3-Phosphoglyceric acid (400 μM; 24 hours; BMDMs) treatment enhances Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification is also reversed.3-Phosphoglyceric treatment significantly augmentes gene expression as well as H3K4me3 deposition of Spp1 in IL-4-stimulated macrophages.In yeast, 3-Phosphoglyceric acid acts as a metabolic checkpoint for the formation of a multicomponent enzyme complex including serine metabolic enzymes and pyruvate kinase isoform 2 (PKM2) homologue, which senses both serine metabolism and glycolysis and regulates H3K4 methylation and histone phosphorylation. RT-PCR Cell Line:Bone marrow-derived macrophages (BMDMs) Concentration:400 μM Incubation Time:24 hours Result:Enhanced Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification was also reversed.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number820-11-1
-
Formula Weight186.06
-
Molecular FormulaC3H7O7P
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(O)C(O)COP(=O)(O)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Zhang W, et al. The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation. J Exp Med. 2018 Dec 3;215(12):3180-3193.?
molnova catalog



related products
-
20-O-Acetylingenol-3...
20-O-Acetylingenol-3-angelate is a natural compound from Euphorbia lathyris L.
-
Theasaponin E1
Theasaponin E1 has antitumor, anti-inflammatory, QR-inducing activity and obesity prevention effects.
-
14:0 PEG2000 PE
14:0 PEG2000 PE (DMPE-PEG2000) is a polyethylene glycol (PEG)-phospholipid conjugate that prevents vesicle aggregation during vesicle formulation and is useful in the preparation of nanostructured lipid carriers.